Could somebody sugest me an in vivo experiment for Inhibitory potential of compounds towards 17beta HSD 2 inhibition?

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How can I ask researchgate to give the number of articles on a specific subjetct?

For a literatura review, I want to know the number of articles on my subject (school drop off) and the research doesn't provide that information

19 April 2024 5,232 1 View

Troubleshooting on thin-layer chromatography (TLC) of fructan-type carbohydrates?

I did thin layer chromatography to identify different types of fructan-type carbohydrates using butanol, acetic acid, isopropanol and water as the eluent (8:4:7:3, respectively). I let the first...

13 November 2022 1,795 0 View

Can addition of any particular glass modifier suppress the crystallization of any particular phase?

Can addition of any glass modifier (like K2O, or MgO ) suppress the crystallization of any particular phase (say, lithium disilicate) in lithium silicate glass system? If so, what is the possible...

18 March 2021 841 5 View

Can addition of glass modifier lower the solidus temperature of a glass composition?

In Li2O-SiO2 glass system a solidus line lies at 1033 deg C between lithium metasilicate + lithium disilicate (S) and lithium metasilicate + liquid (S+L). Can this solidus line be lowered to...

27 September 2020 5,877 3 View

How to measure refractive index of bulk glass sample from UV-VIS spectra?

I have recorded UV-VIS spectra in %R mode (in wavelength range of 200-900 nm) in bulk glass sample. How can I measure refractive index from this data? Thanks in advance, Santa

31 October 2019 4,461 4 View

How I could obtain ER positive normal breast cancer cell lines?

I can not find appropriate/satisfactory (scientific and research-based) information about ER+ normal breast cell line or normal cell line of other reproductive (or non-reproductive) tissue,...

06 July 2019 8,064 4 View

What is the minimum and maximun conductivities to accurately measure zeta potential of polystyrene latexes?

I am working with brine-stable polystyrene latexes, which are colloidally stable at high electrolyte concentration and aggregate in distilled water. I will like to measure the zeta potential of...

22 August 2017 5,143 3 View

What should I do if HPLC pump doesn’t deliver the eluent continuously and the pressure is fluctuating?

I use a reverse phase Waters HPLC. When I used the pump C last week the pressure suddenly fell down from 300 PSI to 0 (with 100% methanol, 0.2 ml/min) for a moment and than went back to 300. I...

18 May 2016 9,678 4 View

Concentration of spatial data, considering the weight, position and distance?

What method I can use to evaluate the concentration of spatial data, considering the weight, position and distance between data?.

21 March 2016 5,388 9 View

Any advice on catch per unit effort with time search of shoals in fishing?

know any fishery that, in the estimation of catch per unit effort incorporate time search of shoals. What unit effort would be advisable to use in trawl fisheries where the fishing trip is long...

21 April 2015 6,702 7 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View

For an in-vitro drug release study, what molecular weight cut-off (MWCO) dialysis bag is required for a 117 kDa protein?

kindly reply me. Thanking you in advance.

05 August 2024 7,727 4 View

Is it true that science is leaving the era of mathematics and entering the era of matrix mechanics?

We assume this to be true. Science leaves the era of mathematics and enters the era of matrix mechanics and the turning point is the discovery of numerical statistical theory called Cairo...

31 July 2024 3,900 2 View

How can you draw a coordinate bond between a metal and donor atom in metal complexes, using discovery studio visulizer software?

Hello,, The metal complex ligand appears incomplete in the screen of the discovery studio visualizer

30 July 2024 3,354 1 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

How to prediction 2D to 3D aptamer?

Hello, I have a little problem. Well, right now I only have the DNA aptamer sequence. I went to see the 2D model form with DNA folding. After that, I used RNA Composer to simulate in 3D and used...

30 July 2024 6,794 0 View

Why in 2D image created by discovery studio 2021, the halogens appear as alkyl group?

In my molecule there is Chloro group at 2-position of phenyl ring, but in 2D image it appears as methyl showing no interaction.

28 July 2024 734 0 View

How can I use DFT-D3 correction ( Siesta version 5.0.1)?

Dear Siesta Users, I installed Siesta 5.0.1 and I want to use Grimme's D3 correction. According to the 5.0.1 manual, I could use a few parameters to include the D3 correction in the...

27 July 2024 5,748 0 View

EDC carbodiimide and NHS easter 's half life among different pH?

It has been long known that EDC carbodiimide and NHS easter's half life agains hydrolysis are highly related to pH. However, very surprisingly, not yet found a paper giving a table/chart of their...

25 July 2024 8,738 0 View

Mechanochemistry: ball to powder mass or ball to powder volume?

I run mechanochemical reactions that involves the use of a large amount of catalyst (1:1 molar ratio to the reactant). When I try to understand the effect of amount of catalyst on the reaction, I...

23 July 2024 9,938 1 View