This is the condition of pre-diabetes. Very often such states are due to insulin resistance and are associated with dyslipidemia, usually of the low HDL-cholesterol and high TG axis, with variable levels of LDL-cholesterol and hypertension. Obesity is usually present.. In of it self, pre-diabetes (also called impaired glucose tolerance) is not related to atherothrombotic disease (ATD) unless dyslipidemia and/or hypertension are present, but should be followed to detect the onset of diabetes mellitus at the earliest time. Of course, to prevent or delay the onset of diabetes, diet and exercise can be employed. Naturally, dyslipidemia and/or hypertension, if extant, should be treated and cigarette smoking must always be proscribed.
Postprandial hyperglycemia is a normal physiological event. The level and duration of the elevated blood glucose level are important in this discussion. If the level remains high after 2 hours postprandial then glucose intolerance must be considered. If the subject exhibits other signs of the metabolic syndrome, then insulin resistance is a consideration.
I agree with all authors comments. Measurement of HbA1C in this condition will be important regarding decision of drug therapy.
I totally agree with the authors. The main author did not elaborate further who is exhibiting the signs. Dietary and life style modification is important in this case. if a gravid woman, interpretation of the glycemic threshold is equally important.
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