Is there a "database-centric" cheminformatics desktop software to manage a large combinatorial DEL library of a billion/trillion diverse molecules? Any advice would be greatly appreciated.
I am trying to replicate results published in the journal paper published recently (Modeling of Laser-assisted micro-milling Inconel718 ). In that paper, they used vdflux subroutine to obtain...
05 July 2024 3,701 0 View
LAH is probably out of the question so maybe H2/Pd could work. But the nitrile would be stabilized due to resonance from the aromatic ring so I do not know if this will work. Of course, we could...
04 March 2024 9,983 1 View
I would like to know the void fraction for known powder material properties to estimate a bisque sample's packing density/void fraction. In combination with any geometric &/or Archimedes...
12 February 2024 9,592 1 View
Hi everyone. I work on Phage display on some protein . I send some sample for sequencing after round 3 and 4 for Phage DNA sequencing. Before sending sample, I check ELISA and data was good like...
08 November 2023 7,339 0 View
What is the equivalent energy of the element Sulphur? with appropriate reference. I need to calculate the energy input from Sulphur fertilizers. Thanks in advance.
05 August 2023 4,731 2 View
I have been using a sliding mode observer (as shown in the attachment). I have designed the gains with the assumption that the derivative of the error (between the state estimates and measured...
06 July 2023 5,301 1 View
I tried ACN, DMSO and other solvent like methanol, water but its seems that peptide is not soluble and it is forming a gel in ACN and water. The peptide has 10-12 amino acid.
02 July 2023 7,323 1 View
Hello everyone, i am working on wideband conformal microwave absorber. I am able to wrap the absorber in cylindrical shape, i am facing no problem. In the case of conical shape the wrapping of...
18 June 2023 4,620 2 View
I have tried to understand the concept but after going through research papers I just couldn't follow up
11 May 2023 799 1 View
Bacteria which show clear on nutrient agar plate and aleksandrov agar plate but act like fungi on the basal medium and pikovskaya agar plate ?
23 March 2023 9,013 1 View
There are a huge number of methods for studying objects in space, according to the senses (and not only). Mechanical, thermal, optical, acoustic, electrical, magnetic, based on particle beams,...
06 August 2024 7,102 0 View
I want to perform a CRISPRa/i library screening for candidate regulatory factors that affect pathogenic Th17 differentiation in PBMC. But I am wondering how to define the size of gene library, so...
31 July 2024 2,150 0 View
When I run autogrid4 it says: autogrid4: ERROR: Unknown receptor type: "Cr" -- Add parameters for it to the parameter library first! Look forward to your reply.Thank you so much!
29 July 2024 488 0 View
How do microbial communities contribute to ecological cycles on Earth and how does an agroecological system support diverse microbial communities?
25 July 2024 5,197 2 View
Dear All, Can somebody share a diversity and inclusion questionnaire for the business context or military context. Thank you Anuradha
22 July 2024 1,320 4 View
> library(meta) Error: package or namespace load failed for ‘meta’ in loadNamespace(i, c(lib.loc, .libPaths()), versionCheck = vI[[i]]): there is no package called ‘numDeriv’
18 July 2024 3,536 0 View
"Today several adjectival phrases have been used to describe English like ‘International Language’, ‘Lingua-Franca’, ‘Language for Globally Connecting’, ‘Library Language’, ‘Official Language’,...
01 July 2024 8,406 5 View
We were using the Zinc database for the virtual compound library in our studies, but there have been problems downloading a large number of compounds for a while. Are there different databases...
30 June 2024 8,144 1 View
I'm analyzing abundances from various ecological surveys. So data was collected across multiple independent years from three sites within each year. The years fall under two temperature...
26 June 2024 2,798 2 View
I have a sequence of ssDNA that I would like to directly ligate an Illumina sequencing adaptor to. As long as I have done the end repair (remove phosphates), can I directly ligate the adaptor to...
26 June 2024 4,522 0 View