Hello i am looking for causes of hyperlactatemia (energetic disorders) with secondary hyperglycinemia (2 times its normal value) , PDH and PC deficit dont fit the profile nor NHK or other causes of hyperflycinemia (normal ketones, normal organic acids); other findings include low glucose (50 mg/dl) and silghtly elevated alanine, isoleucine and leucine, normal renal function. History of seizures, uses Valproic Acid.
Dear Demian,
Maybe the following paper will help you:
Green JP, Berger T, Garg N, Horeczko T, Suarez A, Radeos MS, Hagar Y, Panacek EA. Hyperlactatemia affects the association of hyperglycemia with mortality in nondiabetic adults with sepsis. Acad Emerg Med 2012;19(11):1268-75. http://onlinelibrary.wiley.com/doi/10.1111/acem.12015/epdf
Best wishes from Germany,
Martin
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