Hi Vivek,

It is possible to construct mutant strains of yeast, like Saccharomyces, for simultaneous fermentation of biomass derived pentose and hexose sugars. This is generally done by the introduction of the metabolic pathway for pentose (xylose) metabolism into the wild yeast genome, which does not contain it naturally. However, this does not necessarily resolve all of the complexities associated with pentose fermentation in yeasts, including occurrence of CCR in presence of multiple carbon substrates. I am sharing the link of a recent review article where you will find all details regarding genetic modification of Saccharomyces for co-fermentation of biomass derived mixed sugars.

Article Engineering of Saccharomyces cerevisiae for the efficient co...

You can also consider mixing two pure microbial strains having the capability of fermenting glucose and xylose, like Saccharomyces cerevisiae and Zymomonas mobilis, if you want to co-ferment biomass derived sugars to ethanol.

Regards,

Shiladitya

Thank you for the reply Shiladitya Ghosh.

I will look into the review article and then we can have discussion.