Dear Researchers and Scientists, I would like to know the molecular mechanism behind Cancer-Cell-Specific Nuclear-Targeted Drug Delivery.?

Please suggest any appropriate ligand except hormones

Is it possible to target cell nuclei with amphiphilic lipids or catatonic lipids? If “yes,” please brief the molecular mechanism.?

Some research articles read and found it could be possible by Vitamins-A but no clear evidence about molecular mechanism.

I am looking for a binding ligand that will easily bind with a nucleus receptor-like Type I Nuclear Receptors or Type II Nuclear Receptors.

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