I've been undertaking EEG recordings in the GAERS model of absence seizures which display typical spike-and-wave discharges @ ~6-9Hz interspike frequency. My recordings typically last 30-60 mins during which time there are on average 0.5-2 seizures per minute. The seizures vary in duration from ~1s to ~60s.
Since analyzing by hand (I've just been using Clampfit) is rather time consuming I'd like to run these data through some automated software to tell me (a) what time the seizures occur (b) how long the duration of the seizures and (c) what interspike frequency the spiking occurs at.
Can anyone provide any recommendations for software to perform this that is either free or commercially available?
You can try "Origin Lab Pro v8.5" for seizure spike detection and counting. Peak analysis function of this software is very useful for fast detection of spikes.
Hey Stuart (I think I remember you from Alpbach Meeting last year)
I would recommend Neuroscore from DSI, it also has a bunch of other really cool tools (quantitative, statistical, whatever) for ECoG analysis. I used it for spike detection and qEEG here:
http://onlinelibrary.wiley.com/doi/10.1111/epi.12250/abstract
Stefanie - Thanks for your suggestions. I've been in touch with Dr Van Luijtelaar regarding Spike-and-wave finder; is that the same software as you mention in your second bullet?
Maxine - Thank you also. Yes I remember you from Alpbach too! I'll try the free trial of Neuroscore.
We have written a Matlab script for semi-automated analysis of seizures. Data is imported from a text file with the EEG data as voltage, with a single column for each channel.
It can be downloaded from here:
Code EEG Seizure Analyzer
or here:
https://ninc.centreforbrainhealth.ca/tools
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