You need to know about the specific features of the blood brain barrier delivery in gene therapy and enzyme replacement therapy. Here, I introduce some previous studies as reference, but I leave the discussion open to see what are the experiences of those who conducted research with gene therapy and cerebral circulation disorders.

I think that new approaches for cerebral revascularization through stem cells studies and application can be found too.

Please check the following:

https://www.ahajournals.org/doi/abs/10.1161/str.27.9.1688

Article Gene Transfer to Cerebral Blood Vessels After Subarachnoid Hemorrhage

Article Blood-brain barrier delivery

I think you need textbooks in the following objects:

Neurosciences

Neural pathophysiology

CNS medicine

CNS genotherapy

you can find them as a book or chapters within books...

Best regards

Thank you very much Nashaat

Hi,

Have a look at attached publications of our group; you may find them useful in your research. Let me know if you have any questions related to the manuscripts.

Thank you very much Prof. Mozafari