Can nano-engineered Dendritic cells help to overcome immune tolerance ?

Pradyumna Kumar Mishra @Pradyumna_Mishra2

10 October 2014 1 6K Report

To help overcome immune-tolerance, nano-engineering of Dendritic cells might offer huge potential for clinical translation. We recently devised a Dendritic cell engineering strategy using Solid-Lipid Nanoparticles for developing a therapeutic formulation for gastro-intestinal malignancies. Can anyone suggest alternative nano-materials that could potentially be applied in clinical therapeutic situations ?

Ishak Ozel Tekin

For an adjuvant activity by nanoparticles:

http://www.ncbi.nlm.nih.gov/pubmed/24807558

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