Can crossbreeding Mice lacking apolipoprotein E (apoE-/-) with mice lacking the LDL receptor (LDLR-/-) give offspring with both characteristics?

I want mice model with apolipoprotein E deficiency (apoE-/-) and mice with LDL receptor deficiency (LDLR-/-). Can I get offspring possessing both characteristics by crossbreeding them? or i need...

05 June 2018 1,347 2 View

Can Anyone Suggest an Online Course or Vlog to get Helped With Primer Designing?

I need to design primers for a viral c protein sequence. I need some help to get this done. Please someone suggest if there is any online blog or course.

03 April 2018 7,175 5 View

Any online course suggestion for basic molecular biology techniques?

I am a Masters students who is affirmatively dealing with different basic molecular biology techniques like ELISA, RT PCR, Western Blotting, Northern blotting and etc. I need some online course...

02 March 2018 7,012 3 View

How to monitor oxygen consumption rate in mice model ?

04 May 2016 5,117 2 View

Is any drug available to induce cerebral stroke in mice or rat?

Is their any methods available using drugs to induce stroke in mice or rats leaving surgical intervention and transgenic models???

09 October 2015 4,367 7 View

How to address this issue in the analysis of Real-Time PCR results?

To dear Researchers, I was analyzing a series of concentration for estimation of Real-Time PCR efficiency. The concentration was 1:10. I used MS-excel to evaluate Slope. The result of slope was -8...

01 March 2021 8,683 4 View

Can I download BibExcel for MacOs?

Hi everyone, I would like to ask how I can download BibExcel software for MacOs? There are some links which are supported by Windows but I could not find it for Mac. or is there any other software...

01 March 2021 652 1 View

Anyone with some Transgenomic Wavemaker software? Seeking help from the chromatography community?

I am trying to seek out some Transgenomic Wavemaker software (happy to purchase a computer too) to operate a fraction collector. The only way to connect to the fraction collector so far is to...

23 February 2021 9,181 1 View

I am looking for a simple software program to model 3D chemical bonds. The purpose is to generate high-quality graphical abstracts. Any suggestion?

Hello everyone: I am looking for a simple software program to model chemical bonds. The purpose is to generate a high-quality graphical abstract for a top leading journal in the field of...

23 February 2021 8,012 3 View

Best excel chart to compare algorithms' running time?

Hi I want to compare the running time of robotic path planning algorithms. The grid size is 8X8. I have 100 scenarios of start and goal positions.. Each scenario is run in three obstacles ratio...

22 February 2021 621 1 View

Can't recognize exact phase and PDF card no of Silicon carbide in XRD?

We have deposited silicon carbide on carbon substrate using one PVD technique. Due to amorphous behavior of SiC at low deposition temperature, we performed heat treatment of those films at...

22 February 2021 2,072 3 View

How to increase DPI in my image?

I'm submitting manuscript to a journal that requires 1200 dpi in my images. I have changed the dpi from 96 but when I upload the image with 1200 dpi, the image looks super blurry when I review my...

16 February 2021 2,803 3 View

How to open an old ".MTS" file containing spectroscopic data?

Hi supreme hive-mind of the internet, we have some old *.MTS files that are supposed to contain spectroscopic data, probably some coordinates and a long list of single line spectra. Basically,...

16 February 2021 9,385 2 View

Room Occupancy Calculation ?

15 February 2021 1,997 6 View

How to check if the PMF profile obtained from ABF simulation is correct?

I am doing ABF simulations to calculate ligand binding enegy. The PMF profile that I get using single long ABF simulation is attached as pmf_total.png. When I do this ABF calculation with 10...

10 February 2021 4,170 2 View