Dear Viola, many thanks for sharing this important technical question on RG. As an inorganic chemist I'm absolutely not a specialist in this field. However, I just came across the following potentially useful article. In this study the authors found an association between serum copper concentrations and prevalence of hyperuricemia:

Association between serum copper levels and prevalence of hyperuricemia: a cross-sectional study

https://www.nature.com/articles/s41598-020-65639-0

This paper has been published Open Access (please see attached pdf file). The authoprs also noted that in a previous study no significant association between serum copper concentration and uric acid level was concluded. Please also have a look at this previous study:

Associations of Dietary and Serum Copper with Inflammation, Oxidative Stress, and Metabolic Variables in Adults

https://academic.oup.com/jn/article/138/2/305/4665007

(also see attachment)

I hope this information is helpful for your analysis. Good luck with your research work and best wishes, Frank Edelmann

Dear Frank, Thank you very much for your recommendation! This study is very relevant indeed.

Best wishes, Viola

Excellent answer by dear Prof Frank and fascinating question by dear Dr Viola, yes a few studies followed this hypothesis , along with very related above references, kindly read and follow these papers too;

Wei, F. et al. Associations between serum uric acid and the incidence of hypertension: a Chinese senior dynamic cohort study. J. Transl. Med. 14, 110, https://doi.org/10.1186/s12967-016-0866-0 (2016).

https://www.sciencedirect.com/topics/nursing-and-health-professions/copper-blood-level

and the one which is attached.

Best wishes and Good Luck