Everything you need to know about Fluoride in easy to read format:
Rakita, P.E. (2004) Dentifrice Fluoride. Journal of Chemical Education, Vol. 81, No. 5, pp. 677.
Dear Tony, The hydroxyapatite which comprises to be the principle component of bone and which has biologically evolved to be flexible by nature turns to fluorapatite which is brittle and prone to bending exposure to excessive fluoride ove a period of time.
Fluoride also has a differential affect on our skeletal system. It increases the bone density in axial skeletal system like skull and spine but reduces the bone strength of appendicular skelatal system like hands uptill shoulder blades and legs uptil the pelvic gurdles. Hence vertebra fractures is aided by presence of fluoride but hads and legs become brittle in the presence of excess fluoride!
The normal permissible limit of Fluoride is 1.0-1.5 mg/lit. If it is increased caused fluorosis.. Seriousness of fluorosis varies with concentration of F in water and period of consumption and quantity as well as physical condition of person. Excess F cause to form CaF2 in the body it self which cause to precipitate and thus reduces the Ca from the body. Which intern cause to reduce bone density. Further cause for Osteoporosis.... If F is < 1.mg/lit is not good for dental and gum . It is noted both diseases are incurable if not tackled in time
If fluoride is 2.0 ppm or more in drinking or domestic use water certainly there is high risk for fluorosis and osteoporosis type of diseases. In both the cases decay in bones and gums started. Calcium and Phosphorus and other essential minerals and amino acids etc which are important for giving strength to bones and human body start reducing there activity and bending of bones become major and incurable problem.
Interesting paper:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144112/
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