I've worked for more than one year on the calculation part of my phd work. The theme of my work is ''Searching of low molecular ligands for SH2 domains". I've already finished the whole calculation.
Enamin chemical database (1.6 million compounds) was used as a initial database. In this work I used k-means, ligand- and structure-based pharmacophore models, docking (protein-ligand) and GTM methods. As a result of using those methods 1543 compounds were selected. Now I'm going to do biology testing of whole library or of some part of library. But there are a few problems; I must find the laboratory which will do it and a grant or something else to purchase compounds. If anybody is able to help me with that or has any ideas which will help me, please write them here. I would be very grateful. Furthermore Im very interested in cooperation work.
I think you can apply in you country grants,anotherthing you also apply as project at international donar such,FAO,UNDP
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