from what I came across during my reading: different genes will get activated at different times right?

Brinsko et al. mentioned 6-cell stage.

I'm wondering wherether it is at 6th or 8 cell stage!!

Actually much work in this aspect I could not found from the literature that what I am little bit surprised at and i am not quite sure about this.

thanks for the answer

Hi Thirumala,

I've just submitted my thesis on the embryonic genome activation in non-model species and I've read most of the literature available on this topic. Unfortunately, there is very little on the EGA/ZGA in the horse. The primary reference cited is Brinsko et al. and the 'next best' is "Grøndahl, C., & Hyttel, P. (1996). Nucleologenesis and ribonucleic acid synthesis in preimplantation equine embryos. Biology of reproduction, 55(4), 769-774." Both of these state the EGA occurs at the 6-cell stage. Sorry I can't help you further with this; as far as I know, this area of the field still needs to be investigated.

Jared

Dear Dr Jared Mamrot

thanks a lot for your valuable input/information provided.

Yeah much research needs to be done in this area as it is still unexplored with authenticity