Can anybody tell me the treatment protocol of primary orbital lymphblastic lymphoma without bone marrow involvement?

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No title

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Vlad Kropelnytskyi

T- or B-cell origin?

Luis Villela

You have to treat your patient as acute lymphoblastic leukemia with extranodal involvement.

David J Camilleri

Treat as ALL. If it is B-Cell and expresses CD20 you may add in Rituximab.

Jonas Abrahamsson

Are You absolutely sure that it is not a myeloid neoplasm? It is not unusual for granulocytic sarcoma to locate to the orbit.If so AML therapy is appropriate

If it is preB or T lymphoblastic lymphoma many in Europe would use the Euro-LB02 protocol.

Here is one publication from this protocol

Am J Surg Pathol. 2011 Jun;35(6):836-44. doi: 10.1097/PAS.0b013e318213e90e.

Diagnosis and immunophenotype of 188 pediatric lymphoblastic lymphomas treated within a randomized prospective trial: experiences and preliminary recommendations from the European childhood lymphoma pathology panel.

Oschlies I1, Burkhardt B, Chassagne-Clement C, d'Amore ES, Hansson U, Hebeda K, Mc Carthy K, Kodet R, Maldyk J, Müllauer L, Porwit A, Schmatz AI, Tinguely M, Abramov D, Wotherspoon A, Zimmermann M, Reiter A, Klapper W.