this A-T cells (fibroblasts) sensitivity after ionizing radiation
You should try "Radiation Damage in Biomolecular Systems" - Gustavo Garc a G Mez-Tejedor,Martina Christina Fuss. They explore this topic very well there so, may be you can have a hint going there. A simpler way is just to search the original image on google.
I tried with google but it did not work ... I will try the other way ... Thanks
Dear Hamid
The Figure is a Cell survival curve comparing radiosensitivity of cultured fibroblasts from patients with AT vis a vis normal ones. As you can see, dose for dose they are more sensitive. Moreover, the curves lack a shoulder (the curvature in the initial part of the curve).. One can say that shoulder is due to ability of to accumulate of sublethal damage (SLD), which in turn indicates ability to repair radiation damage. This also confers fractionation sensitivity, ie. up to a particular fraction size, radiosensitivity is not linear; after the shoulder it becomes linear. In short the figure indicates that patients with AT lack ability to repair SLD; hence no shoulder and no fractionation sensitivity.
This figure is probably an old one, because what I said above was established in the 1970s and 1980s. Very likely you will get the figure in Radiobiology for the Radiologist (Eric J Halls) or Fractionation in Radiotherapy (Jolyon Hendry). Or you can get same or very similar figures in articles by Cox, Paterson, etc who were pioneering radiobiologist.: Enhanced radiosensitivity.... M C Paterson et al. Cancer Res 39, 3725-34, Sep, 1979. They give almost same figure and is free to download. Radiosensitivity in Ataxia Telengiectasia by Ling Li.
I am sure that these will serve your purpose
there is an option in the web search engine "google" that permit you to import a picture in order to see all similar pictures and their references.
I hope that this method will be helpful for you
Dear Narayanan, Thanks for your help .... However I did not find the same but actually I found similar photos.
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