Special Issue: Multi-Target Drug Discovery for Complex Diseases Frontiers in Pharmacology: Experimental Pharmacology and Drug Discovery
Complex diseases like cancer, neurodegenerative disorders, diabetes, and cardiovascular disease have intricate and variable causative factors. Computational chemistry, AI, and modern drug discovery methods have enabled the identification of potential modulators for multiple targets from thousands of compounds. These in silico approaches allow the determination of drug-target associations before extensive lab work on chemical synthesis and biological assays. However, these methods rely on the prior identification of clinically and biologically validated targets.
This special issue aims to promote collaboration among clinicians, biologists, AI researchers, and medicinal chemists to advance multi-target drug design for complex diseases.
We welcome original research, reviews, perspectives, and more on themes including:
The goal is to combine computational, chemical, and biological approaches to design new therapies that can effectively treat complex, chronic conditions with fewer side effects. Your contributions to this special issue could help advance more efficacious and timely treatments for patients suffering from these devastating diseases. Please consider submitting your latest research!
https://www.frontiersin.org/research-topics/62267/multi-target-drug-discovery-and-design-for-complex-health-disorders
Important dates:
Manuscript summary deadline: April 28, 2024
Manuscript deadline: August 16, 2024