Dear Colleagues,
Based on clinical and epidemiological data, plant-based diets have emerged as potentially efficacious therapies in the prevention and treatment of various cardiovascular diseases, including, atherosclerosis, hypertension and heart failure. The proposed efficacy of these diets are multifactorial, and include, but are not limited to, (1) the reduction of animal products, which contribute to increased serum low-density lipoprotein (LDL) cholesterol and gut microbial synthesis of trimethylamine N-oxide (TMAO); (2) the increased intake of polyphenols, which have bioactive protective properties at the molecular level; and (3) increased fiber intake, allowing for improved gut microbial diversity and production of beneficial metabolites. However, a paucity of clinical trials and other related human studies have yet to make compelling mechanistic links tying physiological or clinical outcomes with molecular mechanisms. Thus, more research is urgently needed to expand our understanding of how plant-based diets could target CVDs at the molecular or biochemical level.
The purpose of this Special Issue entitled “Plant-based diets in CVD prevention: molecular mechanisms and biochemical insights” is to explore the mechanistic efficacy of plant-based diets in targeting CVD. This Special Issue welcomes articles with an emphasis on clinical research with human subjects. Epidemiological studies and comprehensive reviews are also welcome. While this Special Issue is focused on human research, animal and in vitro studies are also welcome if novel mechanisms are elucidated.
Myself along with Dr. Andrew Gewirtz will be serving as guest editor from the Institute for Biomedical Sciences at Georgia State University.
The link can be found here: https://www.mdpi.com/journal/nutrients/special_issues/C7VV5E75L5
Since the journal is open access, article processing charges will be incurred. Please contact me at my institutional email address [email protected] for a discount.
Article submission deadline is February 15th, 2024.