Can anybody please provide me the in vivo toxicity studies for an isolated compound?

04 May 2016 4,550 0 View

How to measure intraovarian pressure in rats?

What are the laboratory methods available to measure intraovarian and intra abdominal pressure in rats?

06 July 2014 6,192 1 View

What is the best method to induce PCOS in wistar or SD rats?

06 July 2014 8,513 8 View

Can somebody please inform me about the availability and cost of ELISA kits for measuring rat testosterone, estrogen, progesterone, FSH and LH?

06 July 2014 5,477 4 View

Why is cardamom ground along with sugar in food preparations?

Importance of crystal sugar in Ayurvedic preparations.

02 March 2013 7,864 4 View

Aplastic anaemia

Can anybody suggest methods of induction of aplastic anaemia in rats?

02 March 2012 4,386 7 View

Bnezene induced aplastic anaemia

Can benzene cause siezures in rats and thus cause sudden death of an animal?

02 March 2012 1,241 3 View

Can anybody suggest me about the methods available for inducing cancer at very low cost and short duration of time?

Methods available for inducing breast ,intestinal throat and cancer and leukaemia.. In rats or mices..

31 December 2011 6,683 9 View

Can two EC50 values with different hill slopes be compared?

Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...

23 February 2021 8,155 5 View

Is this grounds for theophylline toxicity even though her plasma is within the therapeutic range? if it is, how is that possible?

A patient was given 300 mg Theophylline taken twice a day for the treatment of her bronchial asthma and has a positive clinical response. She has been compliant in taking her medication however,...

09 February 2021 3,489 3 View

Difference between assessing EC50 in presence of physiological levels of human serum albumin and alpha1 acid glycoprotein vs. % human serum?

01 February 2021 1,825 1 View

How can we increase awareness about Covid 19 prevention in our city among the local population?

The general public must be made aware of the mode of transmission, presenting symptoms and the measures that can be undertaken to prevent the spread of infection. Few options- Media, Webinars...

03 January 2021 3,538 13 View

Are the receptor proteins on the surface of infected cells will increase or decrease the susceptibility of antivirals?

Are the receptor proteins on the surface of infected cells will increase or decrease the susceptibility of antivirals?

22 December 2020 3,242 4 View

How to convert Terapeutic Human Doses to Cell Experimentation Doses?

"Toxicological evaluations revealed that Cur is found to be pharmacologically safe, even up to 12 g per day, as reported by several animal studies and in phase-I clinical trials Similarly,...

07 December 2020 3,012 1 View

How to increase presynaptic neurotransmitter release artificially?

I would like to pharmacologically increase presynaptic neurotransmitter release in mice CNS in vivo (through the extracellular micro-infusion of a compound). Which strategy would you recommand?...

02 November 2020 5,645 3 View

No title

30 October 2020 961 3 View

Poly ICLC or Poly IC structure for docking ?

I want to do docking of Poly ICLC with protein. But, unfortunately there is no crystal structure for Poly ICLC or poly IC. Poly ICLC is a complex of Poly IC, poly lysine, and...

24 September 2020 6,107 1 View

Journals accepting book reviews in Pharmacy field (Pharmacology)?

I had published books as a part of my research interest related to pharmacy field (Pharmacology). Now, I am interested to submit books to review in academic journals (Book review publish). Can any...

19 September 2020 1,666 2 View