We are witnessing rise in COVID-19 cases, but the Epidemiological profile of cases seems to have clinical presentation of Common cold only and with very less mortality that too in comorbid conditions like CKD. Still there seems misinformation/ Infodemic going on . Secondly, we are considering genomic surveillance of COVID-19 variants , ignoring other public health challenges including infectious diseases like Tuberculosis with comparatively higher mortality and higher transmission rates including threat of MDR/XDR TB. Thirdly as per some reports we witnessed shortage of drug supply in tuberculosis With monsoon season coming in India ,we in my point of view we should focus on diseases like Dengue, Leptospirosis . To sum up are we ignoring Darwin theory of natural selection in respect of COVID-19?? IS WHO Pandemic treaty should focus on these aspects??