Unhealthy diets that contain bacterial lipopolysaccharides (LPS) promote amyloid beta aggregation and healthy diets in the developing world are encouraged to reduce the toxic amyloid beta speices by release of a number of proteins to prevent amyloid beta aggregation.
Yes . fully agree with Dr. Ian J. Martins expressed views in this regard. Infact unhealthy diets be regulated from the childhood so as to prevent this to happen at a later stage of life.
Hi Ian,
You are correct. "Unhealthy" diets or inflammation inducing diets may indeed cause AB accumulation and are associated with dementia and AD. This article might be helpful: https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-5-37
P.S. "unhealthy" diets or "healthy" diets do not contain LPS. LPS is present in the outer membrane of gram negative bacteria. It is normally used to induce inflammation in animal and in vitro models but not present in food unless this is contaminated.
I hope this helps
It has been reported that oxidative stress could lead to the generation and accumulation of Beta amyloid at the hypocampi of the brain. Unhealthy diet could lead to the generation of free radicals or reactive oxygen species which all hold the strength to mount the stage for oxidative stress, most especially when the antioxidant system of the cells cannot compensate for this condition. This oxidative stress condition could cause the generation of beta amyliod protein and promotes its accumulation, leading to Dementia. Unhealthy diet could lead to Dementia.
The answer appears to be yes. Researchers found Candida yeast in the brains of 11 AD who diet but not in the brains of those who died of other causes. (Pisa D et al. Scientific Reports, 5, 2015).
AB proteins thought to cause AD but now found to block the growth of C. albicans & other brain infections. Therefore, AB is a symptom--not the cause of AD.
Dr. Mark Stengler (Health Revelations 2016) recommends a low glycemic diet, protein, vegetables, pre/probiotic food & multi-strain PBs, S. Boulardii (and antifungal drugs when needed) to help eradicate and keep low C. albicans--therefore preventing the buildup of AB.
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