I want to look at coronary heart disease and mild cognitive impairment for my Masters thesis. I have been told that it is not possible to look at biological pathways/mechanisms - but wasn't given any reasons why.
Can anyone help me shed light on this? I have queried with them.
In my mind I wanted to look at the shared environmental factors (e.g., smoking, diet, physical inactivity), and comorbid conditions (e.g., diabetes, hypertension) - I am aware I dont have access to genetic data so will not be able to include this - but the others seem feasible?
I am planning on conducting a secondary data analysis.
Coronary heart disease and risk for cognitive impairment or dementia: Systematic review and meta-analysis - PubMed (nih.gov)
This review is in fulltext, so read it.
You are going at this the wrong way. You need to start with a question that needs answering, not a topic that interests you.
Read around the literature – the paper linked by S. Béatrice Marianne Ewalds-Kvist is a great start – but focus on questions that need answering that can be answered using data you have access to. This is a masters thesis, too, so don't design a research agenda, just a project that addresses one clear question that can be answered within the time limits and resources available.
I think its wrong to take coronary heart disease with cognitive impairment. Before doing research, you should have a theoretical perspective or strong literature on it. Choose the topic which will make everyone boom, rather than of your interest.
And still if you are interested then make proposal in such a way that please your advisor. Good luck.
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