Dear Dr Elmanama, there are various methods using luminiscence and gen reporters in lux-based QS systems it this point, the LuxR-OHHL complex (3-oxohexanoyl- L -homoserine- lactone and Lux receptor protein)activates gene transcription, useful in bioluminescence methods. Other assa is the measure of amount of violacein, a violet pigment, produced by Chromobacterium violaceum as a result of QS activity. With best regards

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038492

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0093414

. Lowery CA, Salzameda NT, Sawada D, Kaufmann GF, Janda KD (2010)

Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med

Chem 53: 7467-7489.

Marsden DM, Nicholson RL, Skindersoe ME, Galloway WR, Sore HF, et al.

(2010) Discovery of a quorum sensing modulator pharmacophore by 3D small-

molecule microarray screening. Org Biomol Chem 8: 5313-5323.

Christensen QH, Grove TL, Booker SJ, Greenberg EP (2013) A high-throughput

screen for quorum-sensing inhibitors that target acyl-homoserine lactone

synthases. Proc Natl Acad Sci U S A 110: 13815-13820.

Dear Prof.; I found this for you..

Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

Morten Hentzer and Michael Givskov

Center for Biomedical Microbiology, BioCentrum-DTU, Technical University of Denmark (DTU), Lyngby, Denmark

Address correspondence to: Michael Givskov, Center for Biomedical Microbiology, BioCentrum, Building 301, Technical University of Denmark, DK-2800 Lyngby, Denmark. Phone: 45-45252769, or 45-21409867; Fax: 45-45932809; E-mail: [email protected]

i attached two articles .

may be important 

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1063990/

http://www.tandfonline.com/doi/abs/10.1080/08927014.2014.972386?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed#.VG13youUdD4

Using Chromobacterium violaceum as the model organism is the simplest assay.