you can see:

http://www.mathworks.com/discovery/genetic-algorithm.html

http://www.mathworks.com/products/global-optimization/

http://www.mathworks.com/products/global-optimization/features.html#genetic-algorithm-solver

you can see:

http://www.mathworks.com/discovery/genetic-algorithm.html

An Introduction to Genetic Algorithms_Jenna Carr

Applied Optimization with MATLAB Programming By P. Venkataraman

Genetic Algorithms in Search, Optimization, and Machine Learning by David E. Goldberg 

Genetic Algorithms and Engineering Optimization by Mitsuo Gen 

Just try the GA toolbox

Here are some sources would fit your problem,

Also, ANSYS  FLUENT  tutorial in the chapter of 'solvers'  has some information about simulation in PISO under different circumstances.