Why is intravenous injection a kind of systemic drug delivery (what areas cannot this injection method reach when we deliever drug/virus?

Why is intravenous injection a kind of systemic drug delivery (what areas cannot this injection method reach when we deliever drug/virus and what else other methods that could help drug/virus to...

09 October 2018 4,841 4 View

Why cannot we use prokaryotic cells (e.g. E. coli) or yeast or other low-cast cell lines to produce virus particles (e.g. rAAV or lentivirus)?

why

07 August 2018 7,082 0 View

Are there any books or references profiling morphology of various eukaryotic cells (especially mouse/human cells)?

I wish the books or references that could tell me why the morphology of these cells happen and what implications does such morphology will give us under designated conditions.

07 August 2018 4,921 0 View

Are there any websites demonstrating various biological experiments even in deepweb or darkweb (e.g. JoVE)?

experimental videos tend to be more direct sometimes.

07 August 2018 3,487 1 View

How to analyse advanced structure of a protein or protein complex in order to improve protein's some properties?

Are there any real cases in ways of bioimging or bioinformatics?

07 August 2018 5,561 0 View

Does rAAV have a potential risk to integrate a piece of DNA into host genome?

Is it true, statements below? 1. Instead, the rAAV genome is typically processed into a double-stranded circular episome through double stranded synthesis. These episomes can concatemerize,...

07 August 2018 7,208 0 View

Are there any resources introducing the interaction and mechanism of plasmid vector elements when you deliver plasmid into specific cells?

(e-)books, web, database, ......... includes prokaryotic and eukaryotic plasmid vector electments

07 August 2018 1,134 0 View

What molecular and genetic mechanism is that Lac+ E. coli shows red/pink color while Lac- E. coli shows white color on MacConkey plate?

Could you explain this from the level of Lac-associating gene and metabolic process?

05 June 2018 1,027 3 View

Are there any resources, tools, or references that can allow me to understand functions of various plasmid elements?

I know Addgene plasmid 101, only.

04 May 2018 6,418 3 View

Are there any masterpiece teaching synthetic biology especially related with plasmids construction?

Except Addgene plasmid 101

04 May 2018 1,450 3 View

Could you recommend any books about Number Theory?

Beginner level books. High level books. Analytical Number Theory. Algebraic Number Theory. Combinatorical Number Theory. Books about partitions. Books about primes.

03 March 2021 7,174 5 View

What kind of intervention will be relevant to increase motivation among young sport trainees?

Any suggestion on what book to read is also welcome.

03 March 2021 1,646 4 View

How the parameters (such as Mw, Chemical bonds, polymer bland and so on) affect the mechanic property of polymer (such as storage, loss modulus) ?

Anyone can recommend any books on such topics? Thanks in advance.

02 March 2021 8,457 2 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Please suggest a good text book for "Research Methodology in Life Sciences". Which book would be good for PhD Scholars?

Please provide Book Title and author name

02 March 2021 9,059 3 View

Which is a lucid standard comprehensive book to guide on psychological scale construction and its standardization?

02 March 2021 7,082 3 View

What element is driving the different slop in the low frequency tail?

My study consists simple corrosion inhibitors in salty brine. Right now I just fit my circuit with randles with CPE. Just wondering how the slop can given more info of the experiment. Or any...

01 March 2021 6,474 3 View

Does anyone have a recommendation for yeast reporter gene plasmid/protocol?

Hi, could anyone recommend a plasmid and/or protocol for reporter gene assay in S. cerevisiae? I want to assess the effect of growth conditions on a transcription factor, so I want to clone it`s...

01 March 2021 210 1 View

Why might my GFP tag be dissociating from my plasmid after transfection?

I have a set of stably transfected cell lines all transfected with plasmids containing GFP tags on the C terminus. During a western blot using anti-GFP antibody, one of my plasmids has dissociated...

01 March 2021 9,310 4 View

Expression cloning by using cDNA,do I need to modify the cDNA first?

I am going to have a expression cloning of mammalian gene by using shuttle plasmid to transforming the E.coli However I don't know I should only inserting the Coding sequence ,or I can...

28 February 2021 5,440 3 View