Are there any new developments or formulations of rosiglitazone being explored to improve its therapeutic profile?

More Indunil Karunarathna's questions See All

How does neuraxial anesthesia impact postoperative recovery compared to general anesthesia?

The Evolution and Application of Spinal Anesthesia: Techniqu... How does neuraxial anesthesia impact postoperative recovery compared to general anesthesia?

27 June 2024 4,159 1 View

How can ongoing education and team-basedsimulations improve the effective use of normalsaline in clinical practice?

Overview of Normal Saline in Fluid Therapy: Mechanisms, and ... How can ongoing education and team-basedsimulations improve the effective use of normalsaline in clinical practice?

27 June 2024 3,972 1 View

What roles do different healthcare professionals(physicians, nurses, pharmacists) play in themanagement of normal saline therapy?

Overview of Normal Saline in Fluid Therapy: Mechanisms, and ... What roles do different healthcare professionals(physicians, nurses, pharmacists) play in themanagement of normal saline therapy?

27 June 2024 848 1 View

How does normal saline differ from other crystalloidsolutions in terms of composition and clinicalapplication?

Overview of Normal Saline in Fluid Therapy: Mechanisms, and ... How does normal saline differ from other crystalloidsolutions in terms of composition and clinicalapplication?

27 June 2024 4,235 1 View

Why is it important to avoid or carefully managenormal saline use in patients with renal impairment orcongestive heart failure?

Overview of Normal Saline in Fluid Therapy: Mechanisms, and ... Why is it important to avoid or carefully managenormal saline use in patients with renal impairment orcongestive heart failure?

27 June 2024 7,469 1 View

Can you explain the differences between spinal and epidural anesthesia in terms of their mechanisms and clinical applications?

The Evolution and Application of Spinal Anesthesia: Techniqu... Can you explain the differences between spinal and epidural anesthesia in terms of their mechanisms and clinical applications?

27 June 2024 3,166 1 View

What are the primary indications for choosing neuraxial anesthesia over general anesthesia in surgical procedures?

The Evolution and Application of Spinal Anesthesia: Techniqu... What are the primary indications for choosing neuraxial anesthesia over general anesthesia in surgical procedures?

27 June 2024 5,763 1 View

How might future research impact the currentpractices of fluid therapy in critically ill patients?

Overview of Normal Saline in Fluid Therapy: Mechanisms, and ... How might future research impact the currentpractices of fluid therapy in critically ill patients?

27 June 2024 4,458 1 View

What are the key contraindications to neuraxial anesthesia, and how are they managed?

The Evolution and Application of Spinal Anesthesia: Techniqu... What are the key contraindications to neuraxial anesthesia, and how are they managed?

27 June 2024 3,110 1 View

What are some of the most common complications associated with neuraxial anesthesia, and how are they prevented or managed?

The Evolution and Application of Spinal Anesthesia: Techniqu... What are some of the most common complications associated with neuraxial anesthesia, and how are they prevented or managed?

27 June 2024 8,659 1 View

What are the steps of formulating a herbal extract into a sheep/goat drench?

I am working on natural remedies for de-worming in small ruminant livestocks. Part of my project involves formulation of drench-type product, which I have not much experience in. My experience is...

30 July 2024 9,806 1 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

"Dear Researchers, Could anyone here share insights or tips on how to effectively draft a patent in the Nanotechnology field?

"Dear Researchers, I am currently working on a Nanotechnology project and am exploring the process of drafting a patent to protect our innovations. Could anyone here share insights or tips on how...

02 July 2024 9,627 2 View

How can formulate Phosphorus 52 and Potassium 34 in liquid ?

formulate Phosphorus 52 and Potassium 34 in liquid

03 June 2024 7,589 2 View

What are good sources for solvent parameters for modern formulation buffers for DLS?

I am dealing with some finicky antibodies that like to self adhere a bit in certain buffers. Working towards formulation for dosing we are trying to find good buffers that will minimize this...

30 May 2024 6,490 3 View

How to make the PINN for integro-differential equation in Tensorflow?

There is a problem of constructing a PINN based on an integro-differential equation in Tensorflow. Its simplified form is shown on the picture. The function h has no analytical solution. The...

22 May 2024 6,881 4 View

How can I make my graphene ink more spreadable?

I've been working on graphene ink for a while now and have encountered some issues with its spreading on paper. I'm uncertain whether the problem lies in the ink formulations or the size of the...

13 May 2024 9,178 2 View

How to calculate dosing of polyherbal formulation and what quantity of individual herbs should be taken to prepare PHF?

How to calculate dosing of polyherbal formulation and what quantity of individual herbs should be taken to prepare PHF.

02 May 2024 2,796 0 View

Question: Herbicide formulations ?

Which is probably a better and efficient formulation for the application of Pre-emergent herbicide? A) Dry formulation B) Liquid formulation?

11 April 2024 5,157 1 View

How do I prepare a formulation, like an emulsifier concentration from essential oils, ready to use for controlling insect pests in the field?

I will prepare a formulation made from essential oils; are there any procedures or suggestions about that? I would be grateful if you could provide me with some ideas. Thank you,

21 March 2024 4,718 5 View

Indunil Karunarathna

Article Efficacy and Safety of Rosiglitazone in the Management of Ty...

Ljiljana Krsteska

In order to improve the therapeutic profile, it is necessary to use rosiglitazone maleate salt and to take into account the particle size of the API , (D[V, 0.9] 178,38 µm) so that the tablets have a controlled release profile so that supra-bioavailability does not occur.