Are there any new developments or formulations of rosiglitazone being explored to improve its therapeutic profile?

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Detection and Identification of Amanitins in the Wood-Rotting Fungi Galerina fasciculata andGalerina helvoliceps

Dear all, Can anyone help me to contact the corresponding author of the paper " Muraoka, S., Fukamachi, N., Mizumoto, K., & Shinozawa, T. (1999). Detection and Identification of Amanitins in...

01 January 1970 6,517 3 View

Edible mushrooms and their cultivation

Hi All, Does anyone have the PDF of following book? Chang, S. T.; Miles, P. G. (1989). Edible mushrooms and their cultivation. Edible Mushrooms and Their Cultivation, 345. Thanks

01 January 1970 7,851 1 View

How to formulate Energy minimization in Molecular dynamics simulation for alloys using meam potential?

during MD simulation, the atoms are not moving as per required. The problem (as per my observation) lies in energy minimization technique. upon application of tensile strain in x or y direction,...

22 February 2021 380 5 View

Formulate model for one integer optimization?

I am working on one optimization problem. the model with two states, the transition between the two states based on one threshold value (L = 5, which L< 5 -> Normal state, L== 5 ->...

11 February 2021 4,045 3 View

Anyone knows about how to stop pH getting acidic after 7 days formulating the formulation?

i am trying to formulating one formulation but the problem i am facing is after formulating and adjusting it's pH, when i try to check pH after 7 days it is getting down towards the acidic side....

02 February 2021 9,343 3 View

What could be possible reason of higher Drug Concentration of Liposomal formulation stability samples over time?

Hello Everyone! I have prepared liposomal formulation using Rotary Evaporator method followed by dialyzed the liposomal Suspension in Phosphate buffer to remove the un-encapsulated drug. After...

25 January 2021 7,752 4 View

Guide to getting started with semi-solid formulations?

Hello everyone. I'm a pharmaceutical scientist whose experience is exclusively in solid dosage form. I'm starting a project that involves a semi-solid (cream) formulation, but I can't find a lot...

24 January 2021 4,055 3 View

Any HPLC validated method available to separate tricholine citrate and cyproheptadine hydrochloride from any formulation?

Need to have a validated, stable method to separate tricholine citrate and cyproheptadine hydrochloride from a syrup formulation.

20 January 2021 4,216 2 View

What if design and develop some mechanism to eradicate the triggers to achieve data accuracy and achieve assured results?

The realistic approach to identify the exact choices and or preferences is quite difficult seems due to multiple unrealistic profiteering triggers applied to confuse and deviate the end-users from...

25 December 2020 8,304 1 View

How to formulate the dynamics of the body of a legged robot(quadruped/hexapod) ?

I need to formulate the lagrangian dynamic equations for the hexapod robot's body. The body will constitute 6 DoF, which is 3 linear and 3 angular. I have the coordinates of each corner of the...

24 December 2020 1,222 1 View

How do I calculate potency of a working standard for assay evaluation of a Tablet formulation by RP-HPLC?

I have come across a formula to calculate the amount of drug present in a tablet formulation that mentions as such Amount of drug = (Peak area of sample/Peak area of standard) * (Dilution factor...

13 December 2020 4,224 3 View

How do you prevent discolouration(yellow) in white rubber compounds?

The correct combination of ingredients must be used in rubber formulation. Is there another means to prevent discolouration other than reformulating compounds?

03 December 2020 8,960 3 View