I'm interested in performing mid-IR (4-12 um) spectroscopy in microfluidic devices. Are there any spectrometers that can couple into the small volumes and deal with the short time scales present in such devices?
We actually have access to an IR microscope (we're currently building and selling quantum cascade laser based microscopes at my company (see http://daylightsolutions.com/life-sciences/spero.htm), so we can perform spatially resolved spectroscopy on microfluidic devices. But the issue is really time resolution. The microscopes take several minutes to acquire a spectral cube, but we'd like to be able to monitor processes on the sub-second time scale. Part of this is motivated by coupling with LC or capillary systems where elution times can be quite fast. We're looking at a rapid tuning quantum cascade laser spectrometer that could have the optical power and tight focusing to couple into microfluidic channels, and want to see if there are any systems we can benchmark our performance against.