Metabolically engineered strains in the sense of overexpression or deletion of specific genes within their metabolic pathways, enabling the transfer of biosynthesis pathways between different organisms (it may be any eukaryote or prokaryote including archaea).
I need to understand if they fall under the category of GMOs for regulatory purposes.
Kavindu Munugoda
In general, any intentional, targeted manipulation of an organism's genome through insertion, deletion or directed mutagenesis of genes would subject it to GMO oversight and regulations in most jurisdictions. Metabolic engineering strategies that employ these techniques to optimize biosynthesis pathways would need to follow applicable rules for the development, testing, and commercialization of GMOs.
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