To develop methods of reducing development of drug resistance, I would like to understand how different micro-organisms develop resistance to different drugs. Initially, I would like to focus on similarities at molecular level.
To develop methods to reduce development of drug resistance you should focus in specfic kinds of bacteria or fungi. The resistance profiles should be specified first to propose alternative antimicrobial products. Genes of resistance are different for bacteria and Fingi as mechanisms are for almost specific. In order to help you to learn more about I send you here an interesting full paper.
Dear Kabali to reduce the drug resistance the most important pivot is to diminish the drug pressure and in turn the chance of developing the natural selection of microorganism which could be transmitted by vertical or horizontal gene transferring
To develop methods of reducing development of drug resistance, you have to focus on any specific bacteria or fungi. because there is multiple resistance which are showing drug resistance to bacteria and fungi. the resistance pattern is depend on their Horizontal transmission or Vertical Transmission Dynamics in clinical settings/Community and antibiotic pressure.
Thank you Monia El Bour, Zahid Aziz, and Anand Prakash Maurya for the responses provided so far. I am reading in details on the suggestions you have made and will revert with further questions soon. Regards