Why has there been a lack of toxicological research on Phosfolan-methyl since 1966? What recommendations should be followed for conducting a risk assessment for Phosfolan-methyl, considering the lack of toxicological research since 1966?
What would you like to know? It is quite well documented. Do you have a reason to suspect anything has changed since the 1966 research? You may fund or research anything that you like. Apparently, the affected stakeholders are satisfied with the existing information.
Phosfolan apparently has no registrations in the U.S. It was briefly considered in the Registration Standards program in the early 1980s. It appears that no data was submitted to USEPA to support any registrations at that time.
In my opinion, you should conduct a systematic review of this compound's toxicological studies to determine which area should be further explored. If not enough studies are available, you can use risk assessment studies of similar-group compounds as a starting point to begin your research.