William R. Buckley

11 Questions 98 Answers 0 Followers

Questions related from William R. Buckley

Has any reader of this question, access to such neural network or other ML tool that predicts the next symbol given some prior sequence?

I am researching random number generation techniques, and would like to find a neural network or other machine learning software, that is able to track the sequences that my software generates, in...

18 February 2019 9,630 2 View

In what ways does genome architecture reflect cell architecture?

In simple self-replicating machines (exclusive of developmental automata), the structure of the description (machine genome) is very simple. For the von Neumann model, the description is...

11 October 2018 6,501 3 View

To what extent is known any participation of non-active site amino acid residues, they acting as structural components of cells?

I offer the hypothesis that those amino-acid residues that are not part of the active-site, and particularly those found on the outside of the active protein, may perhaps have a role in the...

08 November 2016 5,540 5 View

Is it possible to represent, within a sequence of n digits, a short subsequence that represents each value in [0..n) exactly once, for all n >> 0?

As indicated in other postings I've made, the sub-sequence has a length (number of symbols used to represent the indicated values [0..n)) that is equal to the rounded-up value of log10 n. So, for...

07 February 2015 5,500 43 View

What literature exists respecting crossover point distribution; preference for site of crossover?

I gave Google the search criteria of {regularity crossover site} and obtained less than encouraging results; they suggest that no publication has addressed specifically the question of non-random...

31 August 2014 6,485 5 View

How might, and should, ResearchGate be used to facilitate collaborations, such as by providing hangouts, access to cloud computing, publishing, etc?

The Q&A facility of ResearchGate is a great way for workers to find solutions to vexing problems, make contact with like minded researchers, etc. Yet, it seems a long way from the support that...

14 February 2014 7,752 2 View

Is anyone familiar with this equation, for the number of different microstates of a maximally disordered DNA molecule?

This is the equation: f(n) = [ (4 ^ ( 4 ^ n)) * (3 ^ ( 4 ^ n)) * (2 ^ (4 ^ n)) * (1 ^ (4 ^ n)) ] / 4

05 February 2014 6,476 12 View

Can the set of shustrings for any chromosome be assembled in only one order?

This is to say, the linear ordering of nucleotide residues in the DNA molecule is equivalent to the orderings of nucleotide residues in the set of shustrings. I am looking for commentary on this...

24 January 2014 6,415 6 View

What evidence exists for formation of chiasma across an open reading frame?

Does this occur, or does this not occur? If it does indeed occur, with what frequency?

16 May 2013 4,968 0 View

Can shustring distributions be used as a measure of genome redundancy?

Extending the discussion of shustrings, it occurs to me that indeed this will perhaps be the best measure of sequence redundancy. If it happens that a genome of arbitrary size is of minimal...

16 March 2013 3,820 2 View

The Nature of Law-Based Society: Coercion, Corruption, Hypocrisy. Prove Me Wrong.

I think the title completely describes the question.

01 January 1970 7,737 5 View