Tianhang Li

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Questions related from Tianhang Li

Whether a DNA promoter methylation primer for MSP analysis could be designed on the sites without CpG islands?

Dear everyone, Recently, i am exploring the up-stream regulatory mechanism of a specific oncogene and speculate that this oncogene is pre-transcriptionally-mediated by DNA promoter...

21 December 2021 1,129 0 View

I want to know how to define the pre-metastatic draining lymph node in a tumor-bearing mice model?

Dear everyone, I am now focusing on the mechanisms of cancer lymph node metastasis, especially interested in the pre-metastatic microenvironment of lymph node. However, when I made the mice...

09 August 2021 2,081 3 View

Will the expression of MHC-I complex be up-regulated by the increase of the peptide it need to present?

01 January 1970 8,135 0 View

What is the difference between the innate PD-1-high T cells and the adaptive PD-1-high exhausted T cells in the tumor microenvironment.

Hello! every one! As the basic principle of immune-checkpoint blockade for cancer, re-invigoration of T cell through inhibition of PD-1-PD-L1 pathway leads to enhanced cancer-killing...

01 January 1970 1,069 0 View

The promotive effect of obesity and fat on bladder cancer may be dependent on androgen-related pathways

A recent interesting paper discussed the association between sex and obesity with cancer risk(.Adiposity and sex-specific cancer riskJune2023Cancer Cell 41(6):1186-1197.e4 ). I noticed a very...