6 Questions 17 Answers 0 Followers
Questions related from Sébastien Brûlé
Dear all, I am wondering if someone uses a single point or double point method to determine the intrinsic viscosity of their proteins. These methods are usually developed for polymers and does...
07 August 2020 6,335 5 View
Hello, Our old but not to old DynaPro Plate reader I does not work anymore and Wyatt does not want to investigate the problem as the instrument is 10 years old. We have the money to pay them but...
15 December 2019 6,839 3 View
Hello everyone, We are working on mycolactone and we would like to ionize mycolactone on a MALDI-TOF/TOF mass spectrometer. We have already tested several common matrices such as HCCA, SA, sDHB,...
09 October 2019 574 1 View
Dear all, For some applications in AUC, we would like to correctly determine the partial specific volume of our biomolecules. We currently use Sednterp as a principal approach which diplays a...
24 July 2019 6,124 1 View
I am working with proteins and glycoproteins with a MALDI-TOF instrument for the determination of intact mass. For proteins, I work with SA, sDHB or HCCA depending on the molecular size. Currently...
05 February 2018 3,952 5 View
Hello everyone, My question is the next : Why the DHB matrix is a reducing agent while sDHB matrix is not a reducing agent? In this article it is written that sDHB is a non reducing agent Fast...
20 October 2017 292 3 View
