17 Questions 21 Answers 0 Followers
Questions related from Sandeep Telkar
All RGs I have 3 questions regarding LigPLot? 1. Can I batch process the LigPlot that we run individually (results of virtual screening - same protein different ligand) 2. Where exactly the...
10 October 2016 4,413 1 View
Few of my friends say research on Helicobacter pylori has been banned in India. Is it real? I am in a sort of confusion, because as I googled regarding this, I didn't get any of such information....
07 July 2016 2,960 3 View
Dear RG members, I want to separate silver nanoparticle bound phytochemical from unbound phytochemical during green synthesis. I have tried various RPMs like 5000, 10000, 18000 etc. but at 5000 it...
01 January 2015 4,815 4 View
By subtractive genomics, I have obtained histidine-containing phosphocarrier protein (HPr) as one of the drug targets in a streptococcus strain. It is non-homologous to human proteome. Several...
11 November 2014 5,353 6 View
I want to edit a pdb file by removing the unrequited hetroatoms and chains and again save it in pdb format. Can anyone suggest some user friendly tools to do this?
06 June 2014 5,838 5 View
What is the meaning of the word ensemble in terms of protein structure? Many times it's also used in combination with the concept of druggability of protein. I am unable to understand what it...
11 November 2013 2,851 5 View
I want to draw Venn diagram for 'n' number of sets data using symmetrical ellipses like this: http://en.wikipedia.org/wiki/File:Symmetrical_5-set_Venn_diagram.svg and not Edwards' Venn diagrams...
11 November 2013 2,322 32 View
I am about to start with my thesis writing in bioinformatics. I've been told to follow with IMRaD format for writing. Could you suggest me a few important points in this regard? Kindly attach any...
11 November 2013 4,662 3 View
I have 6 unique pathogen proteins of interest which have unique pathway when compared to host. I want to simulate and quantify the effects of all of these in both presence and absence of them....
07 July 2013 4,165 1 View
I am in search of a FREE tool (or at least free for academics) that can extract GO annotation for a given protein fasta sequence just like Blast2GO?
07 July 2013 2,479 10 View
I am going to perform a local BLAST and want to download human proteome for the same. I searched it in NCBI FTP, so from where can I download the latest version of human proteome data set.
07 July 2013 5,302 3 View
I have a set of pathoproteins and am interested in predicting their druggablity, and have considered the following: 1. Have neglected the proteins that show any hit after performing DELTA-BLAST...
06 June 2013 8,272 2 View
Can anybody tell me the best available tool for identifying synteny blocks among multiple pathogenomes? I have already tried SyMap, I found it to be OK, but I'm still in search of a better tool...
05 May 2013 4,189 5 View
What is the cut off e value to be taken care of while BLASTing pathoprotein against homo sapiens as a host proteome in subtractive genomics? If possible please do provide references for selecting...
05 May 2013 5,952 4 View
I am working on a pathogen. Via synteny based comparison among the strains of the same species I have identified the uniquely expressed genes, that is, genes which are unique to the organism of...
03 March 2012 1,675 4 View
I have performed synteny based comparison of a pathogenome of interest (say X) against the remaining strains of same group. I have then performed domain analysis of putative genes of X and have...
09 September 2011 4,808 0 View
09 September 2011 608 2 View
