10 Questions 38 Answers 0 Followers
Questions related from Rene Mulder
While doing research on genes possibly involved in a specific phenotype, you can run in to several difficulties for the interpretation and classification of mutations found, consequently making...
13 October 2017 8,689 2 View
When you sequenced a gene and you found a variant what should you do to know if this variant is known? In this I would first only like to focus on search through SNP databases. In this regard...
22 October 2015 4,241 2 View
I have recently found a mutation that leads to a premature stopcodon. I now want to know if this mutation could result in nonsense-mediated mRNA decay. Are there ways to do this?
17 December 2014 7,587 5 View
I want to study specific protein sequences to better understand their functional properties. I think that such information from this group of animals may help in this understanding.
16 July 2014 8,886 2 View
I have recently identified a novel mutation, but want to know the age of it. Are there any good methods/servers to do this?
17 June 2014 1,044 6 View
I want to know how two proteins of interst interact with each other by using their homology-based molecular structure. I know from experimental data which part of each protein is required for...
09 April 2014 4,111 10 View
Would like to get some assistance with simulating/estimating the interactions between two proteins to beteer understand structure-function properties.
24 October 2013 5,445 8 View
I want to continue my career in Academia in the field of bioinformatics.
15 October 2013 4,397 3 View
If you have data on phylogenetics, functional divergence and 3d structures, where should you publish it?
11 October 2013 2,436 6 View
There are several servers and software packages that address this question. However, DIVERGE (http://xungulab.com/pub.html) has been most succesful in determining such regions. Unfortunately, I...
13 September 2013 758 17 View