Pawan Basniwal

4 Questions 8 Answers 0 Followers

Questions related from Pawan Basniwal

How can chemical stains be removed after refluxing the reaction mixture?

Stain may be acidic or basic in nature

05 May 2014 3,665 3 View

Can methanol (as a mobile phase component) react with the free phosphate group of an analyte, where 0.1% formic acid is aqueous part of mobile phase in HPLC?

The drug has a free phosphate group; mobile phase 0.1% formic acid and methanol in HPLC. Is it possible that methanol can form an ester with the free phosphate group of the drug (analyte)?

02 February 2013 8,037 1 View

As we know, phosphate buffers should be avoided in LC-MS analysis. What will happen if a drug has a phosphate group in its structure?

LC-MS Analysis

01 January 2013 589 15 View

If triethylamine is used with a C18 column for a prolonged period, what will happen to the C18 column?

Triethylamine interacts with silanols, but when it is used regularly with a C18 column, I think there may be an effect on the life of the column.

01 January 2013 2,029 4 View