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Questions related from Nav Hh
Hi, I was curious to know what factors affect the resolution of a quadrupole mass analyzer. I find a lot of electrical settings that may affect the mass of the ions that are being transmitted. Is...
18 January 2021 5,951 1 View
is it possible that mass spectrometry can tell radical ions or is it not not possible? (Because loss of an electron will result in only 0.0005 Da, there is no instrument with such high...
13 August 2020 7,074 1 View
Hi all, My understanding about the grid used in ToF is it is useful to reduce the broadening due to the varied kinetic energy of the ion. But also it may reduce transmission (90% or less). Is...
08 August 2020 9,501 0 View
Resolving power of TOF increases with longer drift time (mass/delt(mass) = (t/delt(t) using the kinetic energy ((1/2)*mv^2) and potential energy(z*e*V) ). t is the centroid of drift time. delt(t)...
28 September 2018 9,525 6 View
How do people study the oxidation state of divalent metal ions? The difference is number of electrons, which are very small in mass. How do people actually study this experimentally?
10 August 2018 8,039 3 View
Hi all, Just a quick question. I know typically to allow positive ion mode in MS alone, people use acidic buffer and for negative ion mode basic buffer. When coupling LC and MS, how do we induce...
20 February 2017 8,498 6 View
Hi all, Just had a quick question about for most of the buffer system, why is making buffer at pH pKa±1 is recommended? What is the reason behind it? I've seen people violating this rule all the...
14 January 2017 6,696 6 View
Hi all, I am learning a lot of things about the computational biology for the first time. I was curious, with the current technology, what is the possible simulation time range for a research in...
02 January 2017 7,924 4 View
Hi all, My name is Seoyeon. I am preparing metal binding experiment to a protein of interest. It was previously shown that zinc binds to the protein. For some reason I can't tell that the metal...
08 July 2016 1,975 2 View
Hi all, In the field of antibody, I hear a lot about orphan antibody. Are these orphan antibodies simply antibodies that exist but without purpose (e.g., no evident clinical benefits associated...
01 January 1970 8,571 4 View
Hi all, Monoclonal antibody biosimilars are the monoclonal antibody produced from the same standards of pharmacutical quality as the original monoclonal antibody when the patent of the original...
01 January 1970 5,246 2 View