Mel Gibson

11 Questions 19 Answers 0 Followers

Questions related from Mel Gibson

What are some good examples of articles for moderately polar compounds separated by HILIC?

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21 September 2017 5,132 4 View

Is it possibly to test % recovery using purchased standards if no real samples available,/and adding background standard analytes to test specificity?

I am trying to understand validation better. Are real patient samples required to test % recovery and specificity?. I was told that you would need this for electrochemistry because of oxidation/...

18 September 2017 604 3 View

Are there any infra red detectors for HPLC or UV+IR detector for liquid or gas or supercritical fluid chromatography?

Just wondering about their expense to make. Does liquid propulsion cause excess interference in IR?. A multifunctional HPLC that checks for impurities would be more valuable. Does the liquid...

08 September 2017 3,656 4 View

Phenazines and pyocyanin contain a chromophore. What makes it contain a chromophore in its structure?

I know benzene rings in tryptophan at 280nm give the absorption so is this the only criterion for a molecule to possess a chromophore?. Or do the functional groups play a pivotal role along with...

30 August 2017 3,189 5 View

How efficient in plate count are gaurd columns on their own such as C18 based gaurd column or one of a different material such as ion exchange/ HILIC?

"A properly designed guard column does not deteriorate the separation. As a matter of fact, a well designed and well packed guard column using the same material as in the analytical column is a...

27 August 2017 7,004 12 View

What is the sensitivity of hplc uv DAD detector compared the the BDD electrode?

The Boron doped diamond electrode is very sensitive. I need to know how hplc uv DAD compares so that I can perform easy Limit of detection testing without making up too many samples, and even...

27 August 2017 278 4 View

What statistical method do I use to calculate HPLC resolution?

My peaks have a slight peak tailing so half height or half width is appropriate but do I use R = (RT1 - RT2) / [0.5 * (W1 + W2)],...

26 August 2017 1,720 4 View

Is pyocyanin an alkaloid and/ or a phenazine compound and is pyocyanin secreted by plants or similar compounds?.

I do not understand if pyocyanin is a betaine compound (alkaloid group family being zwitterionic at neutral state) then how is it also a phenazine compound?. Is pyocyanin secreted by plants that...

13 August 2017 1,234 2 View

Is it appropriate to run pH 6.5 or higher for HILIC column materials?

I want to try basic conditions for LCMS in negative mode to try to satisfy the different pKa values of my 5 analytes which gear towards acidic and basic. pH5 is fine but the basic analytes can...

05 August 2017 695 2 View

Which phenazines are polar and nonpolar?

How are they related to anthraquinone, anthracine.

05 August 2017 6,356 1 View

Are there any research papers on Pseudomonas aeruginosa time taken for biofilm formation?

Along with which virulence factors produced during that biofilm transition stage from the planktonic cells. Its good that it was found that cells experience shear stress and flow for formation of...

05 August 2017 9,350 4 View