Majd S. Hijjawi

6 Questions 7 Answers 0 Followers

Questions related from Majd S. Hijjawi

How to plot IC50 and Hill CURVE?

I would like to know please what is the best way to plot curve to calculate IC50. for 3 drugs, FRET kinase binding assay was performed through a service provided by a company, as those 3 drugs are...

12 July 2017 9,411 1 View

Is there any engine/software to search by chemical structure or SMILE?

if you have performed drug design procedure, and ended up with certain chemical structures that you suppose they are active hits or drugs against a certain receptor..... is there anyway to search...

31 October 2016 7,924 5 View

How do analyze your IC50 resultS for a newly designed drugs?

Let's say you have designed new drugs (synthetic), and you tested them by invitro enzymatic assay or by MTT assay on normal cells such as fibroblasts of MCF10 or Hela cells... and you also tested...

31 October 2016 5,524 6 View

How can I convert canonical SMILES format to a 2d chemical structure drawing on word document?

I have got a large number of chemical structures to draw, I have them as soft copy in Canonical SMILES form, and in hard copy in a 2D format chemical structure & i need to draw them to be in a...

31 October 2016 9,011 6 View

How can I develop MCF-7 resistance to doxorubicin ?

I am trying to develop MCF-7 breast cancer cells resistant to doxorubicin , I reached 60 nanomolar concentration, the cells are getting resistant but they are not growing anymore , I need to grow...

01 December 2014 7,791 3 View

How can I develop resistance pancreatic adenocarcinoma cells? Is it okay to use medication instead of gemcitabine raw active material by itself ?

If I wanted to develop a resistance pancreatic adenocarcinoma cells, from a panc1 cell-line, against gemcitabine, and I don’t have gemcitabine as a raw active material by itself, I have it as a...

07 October 2014 8,765 5 View