Kulvinder Singh Saini

2 Questions 10 Answers 0 Followers

Questions related from Kulvinder Singh Saini

What are pros and cons of isolating cancer stem cells (CSCs) from established cell lines vs. primary tumors, for targeting CSCs with new drugs?

There are a number of reports for and against isolating CSCs from established cancer cell lines. One of the best work from Prof. Max Wicha lab, where they isolated CSCs from 33 breast cancer cell...

20 April 2016 9,930 4 View

Apart from ob/ob and Leptin mice, which other rodent models of obesity are employed for proof-of-concept studies of small molecule compound(s)?

We would like to evaluate small molecule compound(s), where exact mechanism-of-action is not clear at the moment. We are conducting in vitro studies right now and would like to extend these...

15 March 2015 4,695 3 View