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Questions related from Hajar Alghamdi
I need to couple Dopamine by NH2 end to silica nanoparticles coated by PEG-NH2, but first i need to convert the PEG-NH2 to COOH by using succinic anhydrous ... can you suggest a reaction condition ?
14 February 2021 3,017 4 View
I'm trying to coat my silica NP with diamine PEG, so i used GOPTS to add epoxy group on the surface of the NP then i'll add the PEG. I can not found protocol for SiNP coating PEG, most of the...
14 January 2021 5,101 4 View
I'm preparing silica NP controlling the size by using different concentration of NH4OH. 1- 16.75 ml ethanol. 2-0.5 ml TEOS. 3- NH4OH (0.3- 0.5- 0.75- 1 ml) mixed for 24 hr then evaporate the...
28 November 2020 1,805 13 View
I'm formulating a drug delivery system that could stimulate Dopamine receptor, For that i need to choose cell line that contain D1R and could be simulated using my delivery system... I have read...
21 November 2020 9,276 2 View
Can any one suggest a way to dry silica nanoparticle without loosing its nano-size? usually it become above 200nm after I dry it (by rotavap) while it is 30 nm in the suspension after stopping the...
01 January 1970 6,154 1 View
I'm using MTT assay to identify IC50 for my nanoparticles, which graph type is used to present the data ? why?
01 January 1970 933 1 View
I'm planning to use MPTP and SHSY5Y cell line to model the PD in-vitro. but MPTP will not be metabolised to its neurotoxic form MPP+. Is there any way to do this step to prepare MPP+ then add it...
01 January 1970 4,609 2 View