Hajar Alghamdi

7 Questions 3 Answers 0 Followers

Questions related from Hajar Alghamdi

Reaction condition to convert NH2 to COOH?

I need to couple Dopamine by NH2 end to silica nanoparticles coated by PEG-NH2, but first i need to convert the PEG-NH2 to COOH by using succinic anhydrous ... can you suggest a reaction condition ?

14 February 2021 3,014 4 View

Surface modification of silica nanoparticles with PEG?

I'm trying to coat my silica NP with diamine PEG, so i used GOPTS to add epoxy group on the surface of the NP then i'll add the PEG. I can not found protocol for SiNP coating PEG, most of the...

14 January 2021 5,098 4 View

Silica nanoparticles synthesis using Stober method with size rang 30-50 nm?

I'm preparing silica NP controlling the size by using different concentration of NH4OH. 1- 16.75 ml ethanol. 2-0.5 ml TEOS. 3- NH4OH (0.3- 0.5- 0.75- 1 ml) mixed for 24 hr then evaporate the...

28 November 2020 1,803 13 View

Which neuronal cell line contain D1R?

I'm formulating a drug delivery system that could stimulate Dopamine receptor, For that i need to choose cell line that contain D1R and could be simulated using my delivery system... I have read...

21 November 2020 9,274 2 View

Silica nanoparticles polydispersity

Can any one suggest a way to dry silica nanoparticle without loosing its nano-size? usually it become above 200nm after I dry it (by rotavap) while it is 30 nm in the suspension after stopping the...

01 January 1970 6,153 1 View

Scatter plot or bar chart for MTT assay?

I'm using MTT assay to identify IC50 for my nanoparticles, which graph type is used to present the data ? why?

01 January 1970 931 1 View

Can i convert MPTP to MPP+ in the lab before add it to SHSY5Y.

I'm planning to use MPTP and SHSY5Y cell line to model the PD in-vitro. but MPTP will not be metabolised to its neurotoxic form MPP+. Is there any way to do this step to prepare MPP+ then add it...

01 January 1970 4,607 2 View