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Questions related from Aruna Srinivasan
What does this statement mean - The uptake of substrate at a specific concentration may reflect both Km or Vmax or both. If Km of a transporter is independent of one of its regulator then the...
10 October 2013 568 7 View
If an inhibitor is uncompetitive, i.e inhibits by binding to ES complex, thus decreasing the Km and Vmax value and if another inhibitor is non- competitive, i.e it inhibits by decreasing the...
10 October 2013 5,388 1 View
Considering the fact that the amount of glucose in the intestine is more than 5mM (i.e more than the normal blood plasma concentration), why would there still be an active transport of glucose by...
09 September 2013 7,542 9 View
If one regulator changes Vmax of a transporter and the other regulator works by changing Km, and when both regulators are effectively added, they do not show any additive regulatory effect on the...
09 September 2013 617 21 View
To understand an effect of protein kinase on substrate transport, an inhibition in transport was seen. Analyzing kinetics, the kinase caused decrease in Km of transporter. Indicating that the...
07 July 2013 7,958 4 View
If affinity of a protein changes, it might alter the post translational modification or might add a modification to the protein. How do I find which are the possible changes that occur to affect...
12 December 2012 4,163 7 View
SGLT1 is a high affinity low capacity transporter whereas SGLT2 is a low affinity high capacity transporter, Is there a relation of affinity with capacity?
12 December 2012 6,216 3 View