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Questions related from Alaa Elawni
Calcium hydrogen phosphate is used in drug formulation as an excipient. Once tablet compressed calcium hydrogen phosphate generates dark spots. Why are these spots generated and what about it's...
16 February 2019 4,374 5 View
For conventional tablet dosage form, what are the conditions in which disintegration results can be neglected in case of good dissolution results? please state the reference and link if possible
29 March 2018 2,110 6 View
For a wet granulation pharmaceutical manufacturing process, what is the best to be used as tablet disintegrant: sodium starch glycolate, croscarmellose sodium or crospovidone? Please also provide...
18 March 2018 9,794 4 View
I`m formulating ranitidine hydrochloride dispersible tablets, regarding the extreme bitter taste of the API, the taste should be firstly masked before formulation. If wanted to use for e.g....
11 October 2017 796 4 View
For active pharmaceutical ingredients that are highly affected by temperature ( >25 c ) and humidity( > 50%RH ), what type of excipients are beneficial for protection from the effect of...
08 May 2016 6,271 10 View
For a calcium carbonate + minerals tablets, what are other dissolution methods for Calcium rather than atomic spectrophotometry that would guarantee no interference with the other minerals??
09 March 2016 8,908 0 View
Does minerals powder - such as calcium carbonate - or any other dense powder have any relationship to the appearance of black or grey spots after tablet compression process?? and why ?!
13 February 2016 3,430 0 View
The APIs cannot be provided at larger particle size. Using high conc. of starch paste + povidone sol. increased the hardness a little bit but still low hardness and high friability persist. Is...
05 December 2015 1,185 14 View
Are there any validated methods to undergo assay and dissolution tests for sodium valproate EC tabs rather than the GC method of the BP?
25 November 2015 4,853 1 View
