Will GluC Protease work on a D-aminoacid peptide the same way as an L-aminoacid peptide?

05 May 2018 1 2K Report

If I have a peptide chain/protein made with D-amino acids, would I be able to digest it with a protease like GluC or would I need a special protease for that?

Adriano Mollica

D amino acids usually confer resistance toward proteases. However they only slower the reaction

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