Article Development and characterization of microcapsules containing...
Article Microencapsulation: Concepts, mechanisms, methods and some a...
Please go through above two papers on the concept of micro-encapsulation of microorganisms
Article Development and characterization of microcapsules containing...
Article Microencapsulation: Concepts, mechanisms, methods and some a...
Please go through above two papers on the concept of micro-encapsulation of microorganisms
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/nanoencapsulation
https://pubs.rsc.org/en/content/articlelanding/2020/fo/c9fo02088h#!divAbstract
https://www.scielo.br/scielo.php?pid=S0103-84782014000701304&script=sci_arttext&tlng=en
β-Carotene is a lipophilic bioactive compound, providing significant health benefits. Formulation of β-carotene-enriched functional foods is a challenge, due to its poor stability, sensitivity towards light, temperature, oxygen, and its poor water solubility which leads to low bioaccessibility and bioavailability. Targeted delivery and controlled release of bioactive compounds directly depend on the encapsulating matrix and particle size. This work reports an effective encapsulation of β-carotene in zein matrix with glycerol as stabilizing agent. β-Carotene was encapsulated in zein protein matrix with different core-to-wall ratios (1 : 10, 1 : 50 and 1 : 100) at micro- and nano-level, through spray drying and electrospraying techniques, respectively. A comparative evaluation of processing technique, resulting particle size and its impact on powder flow properties, dissolution, release and absorption behaviour was conducted. Results showed that up to 81% of encapsulation efficiency was achieved for the nanoencapsulated form obtained through the electrospraying technique. Nanoencapsulates showed excellent dissolution behaviour compared to microencapsulates due to reduced particle size and larger surface area. Further, under simulated in vitro gastrointestinal conditions, nanoencapsulates showed faster release than microparticles. Among the three ratios tested, nanoencapsulates at 1 : 50 were found to be optimal with ∼73% encapsulation efficiency, exhibiting faster release giving more bioaccessibility, with 1.29- and 1.36-fold higher permeability than 1 : 10 and 1 : 100 formulations, respectively. Additionally, the 1 : 50 nanoencapsulates gave ∼1.7-fold increased permeability compared to microparticles at the end of 3 h using an ex vivo everted gut sac technique. This study proves the potential of zein nanoparticles for enhanced permeability and bioavailability of β-carotene.
following this link below
https://pubs.rsc.org/en/content/articlelanding/2020/fo/c9fo02088h#!divAbstract
Sonia Morya
There are various methods of nanocapsulation and microencapsulation by the formation of polyelectrolyte complexes, liposomes, preparation by evaporation of the solvent, precipitation, layered deposition, processing in supercritical solutions. Each of the methods may be preferable for nanocapsulation or microencapsulation. If we compare the thermodynamic stability, then the nanocapsulated disperse system is more stable than the microencapsulated one.
i suggest yhis paper
Article Microencapsulation of microbial cells
Kindly check this publication
Microencapsulation and Nanoencapsulation: A Review
https://www.researchgate.net/publication/318501373_Microencapsulation_and_Nanoencapsulation_A_Review
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