In senior's previous paper,he use miRBase to predict the impact of SNP to miRNA binding.But miRBase main function is to use the name of the miRNA or use miRNA similar sequence to search the detail information of the miRNA.In search result,we can know the predicted targets in other prediction website such as Targetscan.If senior is use the sequence search method of the miRBase(Blastn).
This method only consider the similarity between the sequence.But the other prediction website,they will consider much of parameter such as 3'site,seed region etc.I think the prediction method of the miRBase is not very well.Is there any better prediction website to use sequence to predict the targeted miRNA?
Because the miRBase database aims to provide integrated interfaces to comprehensive microRNA sequence data, annotation and predicted gene targets.
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