I am currently working on developing a wound dressing based on PCL fibers. I dissolve PCL in a solvent mix of DMF and THF (1:1) then I add silver sulfadiazine to the polymer mix. However, I noticed after a while the mix turned greyish-color. what are the possible causes of this color change? Would it suggest the decomposition of SSD? noting that I did not face any problems in fiber formation after the color change happened.
Sewar Abuassi If the solution turns gray after adding silver salt, then microparticles of silver are released. One of the components of the solution is a reducing reagent. Do this experiment with reagents purified from reducing agents.
Oleg Novikov thank you for your response! I will try that. However, I have another question. Do reduced silver particles have antimicrobial activity as that of silver sulfadiazine?
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