I noticed there is a new version of the CAVERweb 2.0 interface. I was in a middle of running bunch of my model proteins through it when they decided to update my website... I decided to re run some of my already completed simulations (they are all insect cytochrome P450 models made unsing Alphafold 3)... although the old version would calculate transport analysis for the ligands I studied the new version won't. I know these ligands are processed by the enzymes becasue of my lab results and the old CAVER was confirming that however the new version seems to think my enzyme does not do anything... The overall architecture of the pocket and no. of tunnels appear similiar for both.

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