Do nitrated and aggregated proteins stimulate dendritic cells ?

31 December 2014 1,732 2 View

Can I consider nitrated and aggregated proteins/peptides as immunological adjuvant?

I prepared nitrated and aggregated protein.

31 December 2014 7,338 3 View

Does accumulation of nitrated and aggregated proteins maintain the microinflammation in cronic diseases ?

I used nitrated protein to create inflammation.

01 January 1970 1,951 0 View

COULD PROCALCITONIN BE USED IN THE TREATMENT OF TRAUMA AND INJURY ?

COULD BE USED PROCALCITONIN AS FREE RADICALS NEUTRALISER ? AS INSULIN AND OTHER PEPTIDES ?

01 January 1970 5,800 0 View

Which of the Covid-19 Vaccines would elicit the best immunoprotection and why?

I want to know which of the available Covid-19 Vaccines would elicit the best immunological response and why

02 March 2021 1,388 3 View

Experimental Design: How deal with pseudreplicates with immunological and clinical-chemical paramaeters?

Hello everybody, I am investigating the influence of a toxinon various clinical-chemical and haematological parameters in fish. I have three treatments (control, low dose, high dose) in my...

24 February 2021 1,243 1 View

Looking for advices and tips to improve the staining and the gating strategy in human blood?

Hi, I am staining a human blood with CD19, CD3,CD14 and CD16. My gating strategy in FlowJo goes like this: - First, I gate a general population SSC-A VS FSC-A => Then gate for single cells, =>...

21 February 2021 5,724 4 View

Is there no general protocol for vaccination study?

Hi, I searched vaccination study to know which MLD50 is suitable for influenza virus study in pubmed. But why every vaccination and challenge conditions are different? Is there no guideline or...

16 January 2021 7,984 3 View

How to estimate the extent to which the FE domain should be meshed with explicit elements in Explicit-Implicit Time integration procedure?

I am developing a MATLAB code for shock problem and want to divide the FE domain into explicit and implicit elements (region of domain at vicinity to shock is meshed into explicit elements and...

15 January 2021 1,968 2 View

Any reference to learn numerical methods for Viscoelastic compressible fluids(oil) (CFD)?

I am developing a solver to simulate compression of oil in shock absorber filled with viscoelastic compressible oil. The model will consider the loss due to viscosity which will decide the...

15 January 2021 1,707 1 View

Can you polarize Jurkat cells into different T helper subsets?

I am wondering if anyone has had success with in vitro polarization (via cytokines) of Jurkat cells. My goal is to understand the affect of a drug on Treg induction and differentiation. I...

12 January 2021 3,606 2 View

Will the new COVID-19 strain, identified in England, affect the vaccine?

According to the CDC, the UK variant has an unusually large number of mutations -- 14 changes and 3 deletions in its genetic code that impact the building blocks of its proteins. This virus has 17...

23 December 2020 375 15 View

Can only the spike protein of the virus provide immunity?

Virology, microbiology, immunology, vaccine

21 December 2020 424 16 View

Can somebody recommend me a decent textbook to learn more about signaling pathways and their mechanistic principles in general?

I studied biochemistry and molecular biology in my bachelors and Immunology in my masters. I never came across a suitable course for general signaling pathways and principles. My interest is...

13 December 2020 5,690 5 View