Polylactic acid synthesized by ROP may contain reminants of the catalyst. Who knows the minimum requirements of the catalyst for this polymer to be applied for medical uses?
I have metal-free process for synthesis of PLA from lactic acid. I am attaching them for you. Stannous catalysts especially SnOct2 is approved by Food and Drug Administration to use in ROP of Lactide.
Article Preperation of Poly (Lactic Acid) Nanocomposite via Catalyst...